Use of Magnesium Sulfate for Severe Pre-eclampsia and Eclampsia in Mexico
Council researchers are conducting a study on the use of magnesium sulfate for pregnant women with pre-eclampsia or eclampsia in Mexico.
Pre-eclampsia is an illness that women can get when they are pregnant, although its cause remains unknown. If pre-eclampsia progresses, it can cause eclampsia (with convulsions), organ failure, and death. Pre-eclampsia and eclampsia are the main causes of maternal mortality in Mexico. International evidence has shown that magnesium sulfate is the gold standard for women who suffer from severe pre-eclampsia and eclampsia to prevent or treat convulsions. However, magnesium sulfate is not used routinely for women suffering this illness in Mexican public health services.
Therefore, Council researchers conducted four complementary quantitative and qualitative studies on the use of magnesium sulfate: (1) a survey among physicians from Mexico City hospitals; (2) in-depth interviews with key informants; (3) a chart review of women who died from (pre-)eclampsia in Mexico City; and (4) a similar chart review at the national level.
The results from these studies show that magnesium sulfate still is not used routinely in cases of severe pre-eclampsia/eclampsia. Barriers to its use include physicians’ lack of knowledge and acceptance of magnesium sulfate, drug-related factors (e.g., fear of potentially dangerous side effects), and lack of monitoring and supervision of magnesium sulfate use.
Magnesium sulfate use for the treatment of severe preeclampsia and eclampsia among cases of related maternal deaths: A review of maternal deaths in Mexico (PDF)
Presentation at Global Maternal Health Conference 2010, New Delhi, 30 August-1 September
van Dijk,Marieke G.; Zuniga Uribe,Patricia; Gordillo,Rufina Luna; Reyes Gutierrez,Maria Elena; Valencia,Jorge; Diaz-Olavarrieta,Claudia; Garcia,Sandra G.
Publication date: 2010
Duration: 1/2007 - 12/2009
Jorge Valencia (consultant)
Ministry of Health, Mexico
Ministry of Health, Mexico City
The John D. and Catherine T. MacArthur Foundation